| Short Description : | Rabbit monoclonal Protein Phosphatase 1e (500-600) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S5751RM |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPM1E |
| Gene ID: | 22843 |
| Uniprot ID: | PPM1E_HUMAN |
| Immunogen Region: | 500-600 |
| Immunogen Sequence: | ESDWTENSFQGGQEDGGDDK ENHGECKRPWPQHQCSAPAD LGYDGRVDSFTDRTSLSPGS QINVLEDPGYLDLTQIEASK PHSAQFLLPVEMFGPGAPKK A |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human PPM1E (Q8WY54). |
| Function | Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2. |
| Protein Name | Protein Phosphatase 1eCa(2+/Calmodulin-Dependent Protein Kinase Phosphatase NCamkp-NCamkp-NucleusCamknPartner Of Pix 1Partner Of Pix-AlphaPartner Of Pixa |
| Database Links | Reactome: R-HSA-9617324 |
| Cellular Localisation | NucleusCytoplasmA Truncated FormMajor FormWith The C-Terminal Part MissingIs Mostly Found In The Cytoplasm And A Little In The NucleusThe Full-LengthMinor FormIs Found In The Nucleus |
| Alternative Antibody Names | Anti-Protein Phosphatase 1e antibodyAnti-Ca(2+/Calmodulin-Dependent Protein Kinase Phosphatase N antibodyAnti-Camkp-N antibodyAnti-Camkp-Nucleus antibodyAnti-Camkn antibodyAnti-Partner Of Pix 1 antibodyAnti-Partner Of Pix-Alpha antibodyAnti-Partner Of Pixa antibodyAnti-PPM1E antibodyAnti-CAMKN antibodyAnti-KIAA1072 antibodyAnti-POPX1 antibody |
Information sourced from Uniprot.org
