| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (1350-1400 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPIP5K1 |
| Gene ID: |
9677 |
| Uniprot ID: |
VIP1_HUMAN |
| Immunogen Region: |
1350-1400 aa |
| Specificity: |
This antibody detects endogenous levels of VIP1 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human VIP1 at the amino acid range 1350-1400 |
| Function | Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4. Activated when cells are exposed to hyperosmotic stress. |
| Protein Name | Inositol Hexakisphosphate And Diphosphoinositol-Pentakisphosphate Kinase 1Diphosphoinositol Pentakisphosphate Kinase 1Histidine Acid Phosphatase Domain-Containing Protein 2aIp6 KinaseInositol Pyrophosphate Synthase 1Insp6 And Pp-Ip5 Kinase 1Vip1 HomologHsvip1 |
| Database Links | Reactome: R-HSA-1855167 |
| Cellular Localisation | CytoplasmCytosolCell MembraneRelocalizes To The Plasma Membrane Upon Activation Of The Ptdins 3-Kinase Pathway |
| Alternative Antibody Names | Anti-Inositol Hexakisphosphate And Diphosphoinositol-Pentakisphosphate Kinase 1 antibodyAnti-Diphosphoinositol Pentakisphosphate Kinase 1 antibodyAnti-Histidine Acid Phosphatase Domain-Containing Protein 2a antibodyAnti-Ip6 Kinase antibodyAnti-Inositol Pyrophosphate Synthase 1 antibodyAnti-Insp6 And Pp-Ip5 Kinase 1 antibodyAnti-Vip1 Homolog antibodyAnti-Hsvip1 antibodyAnti-PPIP5K1 antibodyAnti-HISPPD2A antibodyAnti-IP6K antibodyAnti-IPS1 antibodyAnti-KIAA0377 antibodyAnti-VIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
