Anti-PPFIA1 antibody (660-800) (STJ112424)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPFIA1 (660-800) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPFIA1 |
| Gene ID | 8500 |
| Uniprot ID | LIPA1_HUMAN |
| Immunogen Region | 660-800 |
| Immunogen Sequence | IESRVGSGSLDNLGRFRSMS SIPPYPASSLASSSPPGSGR STPRRIPHSPAREVDRLGVM TLLPPSREEVRDDKTTIKCE TSPPSSPRALRLDRLHKGAL HTVSHEDIRDIRNSTGSQDG PVSNPSSSNSSQDSLHKAPK K |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human PPFIA1 (NP_003617.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. |
| Protein Name | Liprin-Alpha-1Lar-Interacting Protein 1Lip-1Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-1Ptprf-Interacting Protein Alpha-1 |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-181430Reactome: R-HSA-210500Reactome: R-HSA-212676Reactome: R-HSA-264642Reactome: R-HSA-388844 |
| Cellular Localisation | CytoplasmCell CortexColocalizes With Ptprf Near Focal Adhesions |
| Alternative Antibody Names | Anti-Liprin-Alpha-1 antibodyAnti-Lar-Interacting Protein 1 antibodyAnti-Lip-1 antibodyAnti-Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-1 antibodyAnti-Ptprf-Interacting Protein Alpha-1 antibodyAnti-PPFIA1 antibodyAnti-LIP1 antibody |
Information sourced from Uniprot.org