Anti-PPCEL antibody [R02-3I8] (STJA0035330)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human PPCEL/PREPL
General Information
| Short Description | Rabbit monoclonal anti-PPCEL for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-3I8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PREPL |
| Gene ID | 9581 |
| Uniprot ID | PPCEL_HUMAN |
| Immunogen | A synthetic peptide of human PPCEL/PREPL |
Additional Info
| Tissue Specificity | Expressed in pyramidal neurons of the temporal cortex and neocortex (at protein level). Widely expressed. Expressed at higher level in brain, skeletal muscle, heart and kidney. Expressed at the endplates in the neuromuscular junction. |
| Function | Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis. |
| Protein Name | Prolyl Endopeptidase-LikeProlylendopeptidase-Like |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolGolgi ApparatusTrans-Golgi NetworkCytoskeletonNucleusCo-Localizes With Ap-1 In The Trans-Golgi NetworkCo-Localizes With Map2 And Actb On The CytoskeletonCo-Localizes With Stx6 And Gosr2 At The Golgi Apparatus |
| Alternative Antibody Names | Anti-Prolyl Endopeptidase-Like antibodyAnti-Prolylendopeptidase-Like antibodyAnti-PREPL antibodyAnti-KIAA0436 antibody |
Information sourced from Uniprot.org