• Immunohistochemistry of rat tissue with Anti-POMT1 primary antibody (STJ502579) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-POMT1 antibody (400-460) (STJ502579)

SKU:
STJ502579-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-POMT1 (400-460) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: POMT1
Gene ID: 10585
Uniprot ID: POMT1_HUMAN
Immunogen Region: 400-460
Immunogen: Synthetic peptide taken within amino acid region 400-460 on human POMT1 protein.
Tissue Specificity Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver.
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins.
Protein Name Protein O-Mannosyl-Transferase 1
Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1
Database Links Reactome: R-HSA-5083629
Reactome: R-HSA-5083633
Reactome: R-HSA-5173105
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Protein O-Mannosyl-Transferase 1 antibody
Anti-Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 antibody
Anti-POMT1 antibody

Information sourced from Uniprot.org

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