| Tissue Specificity | Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Protein Name | Protein O-Mannosyl-Transferase 1Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 |
| Database Links | Reactome: R-HSA-5083629Reactome: R-HSA-5083633Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Mannosyl-Transferase 1 antibodyAnti-Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 antibodyAnti-POMT1 antibody |
Information sourced from Uniprot.org
