Anti-POLR1E antibody (Internal) (STJ95175)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human POLR1E.
General Information
| Short Description | Rabbit polyclonal anti-DNA-directed RNA polymerase I subunit RPA49 (Internal) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POLR1E |
| Gene ID | 64425 |
| Uniprot ID | RPA49_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human POLR1E. |
| Immunogen Region | Internal |
| Specificity | POLR1E Polyclonal Antibody detects endogenous levels of POLR1E protein. |
Additional Info
| Function | Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF. |
| Protein Name | Dna-Directed Rna Polymerase I Subunit Rpa49Rna Polymerase I Subunit A49Dna-Directed Rna Polymerase I Subunit ERna Polymerase I-Associated Factor 1Rna Polymerase I-Associated Factor 53 |
| Database Links | Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Dna-Directed Rna Polymerase I Subunit Rpa49 antibodyAnti-Rna Polymerase I Subunit A49 antibodyAnti-Dna-Directed Rna Polymerase I Subunit E antibodyAnti-Rna Polymerase I-Associated Factor 1 antibodyAnti-Rna Polymerase I-Associated Factor 53 antibodyAnti-POLR1E antibodyAnti-PAF53 antibodyAnti-PRAF1 antibody |
Information sourced from Uniprot.org