| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNA-directed RNA polymerase I subunit RPA49 (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POLR1E |
| Gene ID: |
64425 |
| Uniprot ID: |
RPA49_HUMAN |
| Immunogen Region: |
Internal |
| Specificity: |
POLR1E Polyclonal Antibody detects endogenous levels of POLR1E protein. |
| Immunogen: |
Synthesized peptide derived from the Internal region of human POLR1E. |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF. |
| Protein Name | Dna-Directed Rna Polymerase I Subunit Rpa49Rna Polymerase I Subunit A49Dna-Directed Rna Polymerase I Subunit ERna Polymerase I-Associated Factor 1Rna Polymerase I-Associated Factor 53 |
| Database Links | Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Dna-Directed Rna Polymerase I Subunit Rpa49 antibodyAnti-Rna Polymerase I Subunit A49 antibodyAnti-Dna-Directed Rna Polymerase I Subunit E antibodyAnti-Rna Polymerase I-Associated Factor 1 antibodyAnti-Rna Polymerase I-Associated Factor 53 antibodyAnti-POLR1E antibodyAnti-PAF53 antibodyAnti-PRAF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
