• Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of lysates from 293 cells, using DNA Polymerase lambda Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using DNA pol Lambda Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-POLL antibody (451-500 aa) (STJ92743)

SKU:
STJ92743

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNA polymerase lambda (451-500 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: POLL
Gene ID: 27343
Uniprot ID: DPOLL_HUMAN
Immunogen Region: 451-500 aa
Specificity: DNA pol Lambda Polyclonal Antibody detects endogenous levels of DNA pol Lambda protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DNA Polymerase lambda at the amino acid range 451-500
Function DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Protein Name Dna Polymerase Lambda
Pol Lambda
Dna Polymerase Beta-2
Pol Beta2
Dna Polymerase Kappa
Database Links Reactome: R-HSA-5693571
Cellular Localisation Nucleus
Chromosome
Accumulates At Sites Of Dna Damage
Alternative Antibody Names Anti-Dna Polymerase Lambda antibody
Anti-Pol Lambda antibody
Anti-Dna Polymerase Beta-2 antibody
Anti-Pol Beta2 antibody
Anti-Dna Polymerase Kappa antibody
Anti-POLL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance