Anti-POLE2 antibody (1-290) (STJ114708)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal POLE2 (1-290) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POLE2 |
| Gene ID | 5427 |
| Uniprot ID | DPOE2_HUMAN |
| Immunogen Region | 1-290 |
| Immunogen Sequence | MAPERLRSRALSAFKLRGLL LRGEAIKYLTEALQSISELE LEDKLEKIINAVEKQPLSSN MIERSVVEAAVQECSQSVDE TIEHVFNIIGAFDIPRFVYN SERKKFLPLLMTNHPAPNLF GTPRDKAEMFRERYTILHQR THRHELFTPPVIGSHPDESG SKFQLKTIETLLGSTTKIGD AIVLGMITQLKEGKFFLEDP TGTVQLDLSKAQFHSGLYTE ACFVLAEGWFEDQVFHVNA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2). |
Additional Info
| Function | Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication. |
| Protein Name | Dna Polymerase Epsilon Subunit 2Dna Polymerase Ii Subunit 2Dna Polymerase Epsilon Subunit B |
| Database Links | Reactome: R-HSA-110314Reactome: R-HSA-5651801Reactome: R-HSA-5656169Reactome: R-HSA-5685942Reactome: R-HSA-5696397Reactome: R-HSA-5696400Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-68952Reactome: R-HSA-68962 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Polymerase Epsilon Subunit 2 antibodyAnti-Dna Polymerase Ii Subunit 2 antibodyAnti-Dna Polymerase Epsilon Subunit B antibodyAnti-POLE2 antibodyAnti-DPE2 antibody |
Information sourced from Uniprot.org