| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Pogo transposable element with ZNF domain is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POGZ |
| Gene ID: |
23126 |
| Uniprot ID: |
POGZ_HUMAN |
| Specificity: |
POGZ Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. Promotes the repair of DNA double-strand breaks through the homologous recombination pathway. |
| Protein Name | Pogo Transposable Element With Znf DomainSuppressor Of Hairy Wing Homolog 5Zinc Finger Protein 280eZinc Finger Protein 635 |
| Cellular Localisation | NucleusChromosomeCytoplasmAccording To Some AuthorsIt Is Not Localized To Mitotic ChromatinRecruited To Trimethylated 'Lys-9' Of Histone H3 (H3k9me3) |
| Alternative Antibody Names | Anti-Pogo Transposable Element With Znf Domain antibodyAnti-Suppressor Of Hairy Wing Homolog 5 antibodyAnti-Zinc Finger Protein 280e antibodyAnti-Zinc Finger Protein 635 antibodyAnti-POGZ antibodyAnti-KIAA0461 antibodyAnti-SUHW5 antibodyAnti-ZNF280E antibodyAnti-ZNF635 antibodyAnti-Nbla00003 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
