| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein O-glucosyltransferase 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POGLUT1 |
| Gene ID: |
56983 |
| Uniprot ID: |
PGLT1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of KTELC1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human KTELC1 |
| Function | Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane. |
| Protein Name | Protein O-Glucosyltransferase 1Cap10-Like 46 Kda ProteinHclp46Ktel Motif-Containing Protein 1Myelodysplastic Syndromes Relative ProteinO-Glucosyltransferase Rumi HomologHrumiProtein O-Xylosyltransferase Poglut1 |
| Database Links | Reactome: R-HSA-1912399 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Protein O-Glucosyltransferase 1 antibodyAnti-Cap10-Like 46 Kda Protein antibodyAnti-Hclp46 antibodyAnti-Ktel Motif-Containing Protein 1 antibodyAnti-Myelodysplastic Syndromes Relative Protein antibodyAnti-O-Glucosyltransferase Rumi Homolog antibodyAnti-Hrumi antibodyAnti-Protein O-Xylosyltransferase Poglut1 antibodyAnti-POGLUT1 antibodyAnti-C3orf9 antibodyAnti-CLP46 antibodyAnti-KTELC1 antibodyAnti-MDSRP antibodyAnti-MDS010 antibodyAnti-UNQ490 antibodyAnti-PRO1006 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
