Anti-PMVK antibody (1-192) (STJ115804)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PMVK (1-192) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PMVK |
| Gene ID | 10654 |
| Uniprot ID | PMVK_HUMAN |
| Immunogen Region | 1-192 |
| Immunogen Sequence | MAPLGGAPRLVLLFSGKRKS GKDFVTEALQSRLGADVCAV LRLSGPLKEQYAQEHGLNFQ RLLDTSTYKEAFRKDMIRWG EEKRQADPGFFCRKIVEGIS QPIWLVSDTRRVSDIQWFRE AYGAVTQTVRVVALEQSRQQ RGWVFTPGVDDAESECGLDN FGDFDWVIENHGVEQRLEEQ LENLIEFIRSRL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human PMVK (NP_006547.1). |
Additional Info
| Tissue Specificity | Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung. |
| Function | Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites. |
| Protein Name | Phosphomevalonate KinasePmkaseHpmk |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Phosphomevalonate Kinase antibodyAnti-Pmkase antibodyAnti-Hpmk antibodyAnti-PMVK antibodyAnti-PMKI antibody |
Information sourced from Uniprot.org