Anti-PMPCA antibody (456-525) (STJ112006)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PMPCA (456-525) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PMPCA |
| Gene ID | 23203 |
| Uniprot ID | MPPA_HUMAN |
| Immunogen Region | 456-525 |
| Immunogen Sequence | TRSRKLPHELCTLIRNVKPE DVKRVASKMLRGKPAVAALG DLTDLPTYEHIQTALSSKDG RLPRTYRLFR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 456-525 of human PMPCA (NP_055975.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis. |
| Function | Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. |
| Protein Name | Mitochondrial-Processing Peptidase Subunit AlphaAlpha-MppInactive Zinc Metalloprotease AlphaP-55 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8949664Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Mitochondrial-Processing Peptidase Subunit Alpha antibodyAnti-Alpha-Mpp antibodyAnti-Inactive Zinc Metalloprotease Alpha antibodyAnti-P-55 antibodyAnti-PMPCA antibodyAnti-INPP5E antibodyAnti-KIAA0123 antibodyAnti-MPPA antibody |
Information sourced from Uniprot.org