Anti-PMPCA antibody (456-525) (STJ112006)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ112006
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General Information

Short DescriptionRabbit polyclonal PMPCA (456-525) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPMPCA
Gene ID23203
Uniprot IDMPPA_HUMAN
Immunogen Region456-525
Immunogen SequenceTRSRKLPHELCTLIRNVKPE DVKRVASKMLRGKPAVAALG DLTDLPTYEHIQTALSSKDG RLPRTYRLFR
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 456-525 of human PMPCA (NP_055975.1).

Additional Info

Tissue Specificity Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.
Function Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Protein Name Mitochondrial-Processing Peptidase Subunit Alpha
Alpha-Mpp
Inactive Zinc Metalloprotease Alpha
P-55
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8949664
Reactome: R-HSA-9837999
Cellular Localisation Mitochondrion Matrix
Mitochondrion Inner Membrane
Alternative Antibody Names Anti-Mitochondrial-Processing Peptidase Subunit Alpha antibody
Anti-Alpha-Mpp antibody
Anti-Inactive Zinc Metalloprotease Alpha antibody
Anti-P-55 antibody
Anti-PMPCA antibody
Anti-INPP5E antibody
Anti-KIAA0123 antibody
Anti-MPPA antibody

Information sourced from Uniprot.org

Citations

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