• Western blot analysis of extracts of various cell lines, using Plexin A1 Rabbit monoclonal antibody (STJ11101931) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-PLXNA1 antibody (100-200) [S1MR] (STJ11101931)

SKU:
STJ11101931

£212.50 - £501.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Plexin A1 (100-200) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLXNA1
Gene ID: 5361
Uniprot ID: PLXA1_HUMAN
Immunogen Region: 100-200
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Plexin A1 (Q9UIW2).
Immunogen Sequence: SVQSCPHGLGSTDNVNKLLL LDYAANRLLACGSASQGICQ FLRLDDLFKLGEPHHRKEHY LSSVQEAGSMAGVLIAGPPG QGQAKLFVGTPIDGKSEYFP T
Tissue Specificity Detected in fetal brain, lung, liver and kidney.
Function Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Protein Name Plexin-A1
Semaphorin Receptor Nov
Database Links Reactome: R-HSA-399954
Reactome: R-HSA-399955
Reactome: R-HSA-399956
Reactome: R-HSA-416700
Reactome: R-HSA-9013405
Reactome: R-HSA-9696273
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Plexin-A1 antibody
Anti-Semaphorin Receptor Nov antibody
Anti-PLXNA1 antibody
Anti-NOV antibody
Anti-PLXN1 antibody

Information sourced from Uniprot.org

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