| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLVAP (63-442) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLVAP |
| Gene ID: |
83483 |
| Uniprot ID: |
PLVAP_HUMAN |
| Immunogen Region: |
63-442 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 63-442 of human PLVAP (NP_112600.1). |
| Immunogen Sequence: |
TERRAEGLYSQLLGLTASQS NLTKELNFTTRAKDAIMQMW LNARRDLDRINASFRQCQGD RVIYTNNQRYMAAIILSEKQ CRDQFKDMNKSCDALLFMLN QKVKTLEVEIAKEKTICTKD KESVLLNKRVAEEQLVECVK TRELQHQERQLAKEQLQKVQ ALCLPLDKDKFEMDLRNLWR DSIIPRSLDNLGYNLYHPLG SELASIRRACDHMPSLMSSK VEELARSLRADIERVAREN |
| Tissue Specificity | Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium. |
| Function | Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development. |
| Protein Name | Plasmalemma Vesicle-Associated ProteinFenestrated Endothelial-Linked Structure ProteinPlasmalemma Vesicle Protein 1Pv-1 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinMembraneCaveolaCytoplasmPerinuclear RegionMembrane-Associated Protein Of CaveolaeFound In Fenestral And Stomatal Diaphragms In Fenestrated Endothelia And Transendothelial ChannelsAlso Colocalized With Cav1 In Perinuclear Region |
| Alternative Antibody Names | Anti-Plasmalemma Vesicle-Associated Protein antibodyAnti-Fenestrated Endothelial-Linked Structure Protein antibodyAnti-Plasmalemma Vesicle Protein 1 antibodyAnti-Pv-1 antibodyAnti-PLVAP antibodyAnti-FELS antibodyAnti-PV1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
