Anti-PLOD2 antibody (260-380) [S4678RM] (STJ11104678)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Procollagen-Lysine-2-Oxoglutarate 5-Dioxygenase 2 (260-380) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4678RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:10000-1:30000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLOD2 |
| Gene ID | 5352 |
| Uniprot ID | PLOD2_HUMAN |
| Immunogen Region | 260-380 |
| Immunogen Sequence | ILLNYFGNYVPNSWTQDNGC TLCEFDTVDLSAVDVHPNVS IGVFIEQPTPFLPRFLDILL TLDYPKEALKLFIHNKEVYH EKDIKVFFDKAKHEIKTIKI VGPEENLSQAEARNMGMDFC R |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 260-380 of human PLOD2/LH2 (NP_000926.2). |
Additional Info
| Tissue Specificity | Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta. |
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Protein Name | Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2Lysyl Hydroxylase 2Lh2 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Rough Endoplasmic Reticulum MembranePeripheral Membrane ProteinLumenal Side |
| Alternative Antibody Names | Anti-Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2 antibodyAnti-Lysyl Hydroxylase 2 antibodyAnti-Lh2 antibodyAnti-PLOD2 antibody |
Information sourced from Uniprot.org