Anti-PLIN3 antibody (135-434) (STJ116409)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PLIN3 (135-434) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLIN3 |
| Gene ID | 10226 |
| Uniprot ID | PLIN3_HUMAN |
| Immunogen Region | 135-434 |
| Immunogen Sequence | MVSSAKDTVATQLSEAVDAT RGAVQSGVDKTKSVVTGGVQ SVMGSRLGQMVLSGVDTVLG KSEEWADNHLPLTDAELARI ATSLDGFDVASVQQQRQEQS YFVRLGSLSERLRQHAYEHS LGKLRATKQRAQEALLQLSQ VLSLMETVKQGVDQKLVEGQ EKLHQMWLSWNQKQLQGPEK EPPKPEQVESRALTMFRDIA QQLQATCTSLGSSIQGLPTN VKDQVQQARRQVEDLQATF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 135-434 of human PLIN3 (NP_005808.3). |
Additional Info
| Post Translational Modifications | Phosphorylation at Tyr-251 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. |
| Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. |
| Protein Name | Perilipin-347 Kda Mannose 6-Phosphate Receptor-Binding Protein47 Kda Mpr-Binding ProteinCargo Selection Protein Tip47Mannose-6-Phosphate Receptor-Binding Protein 1Placental Protein 17Pp17 |
| Database Links | Reactome: R-HSA-163560Reactome: R-HSA-6811440Reactome: R-HSA-9613354Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9706019 |
| Cellular Localisation | Lipid DropletEndosome MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmMembrane Associated On EndosomesDetected In The Envelope And The Core Of Lipid Bodies And In Lipid Sails |
| Alternative Antibody Names | Anti-Perilipin-3 antibodyAnti-47 Kda Mannose 6-Phosphate Receptor-Binding Protein antibodyAnti-47 Kda Mpr-Binding Protein antibodyAnti-Cargo Selection Protein Tip47 antibodyAnti-Mannose-6-Phosphate Receptor-Binding Protein 1 antibodyAnti-Placental Protein 17 antibodyAnti-Pp17 antibodyAnti-PLIN3 antibodyAnti-M6PRBP1 antibodyAnti-TIP47 antibody |
Information sourced from Uniprot.org