Western blot analysis of various lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000

Anti-PLD4 antibody (STJ99651)

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STJ99651
$64.80 - $340.20
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-5 3 exonuclease PLD4 is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLD4
Gene ID: 122618
Uniprot ID: PLD4_HUMAN
Specificity: This antibody detects endogenous levels of PLD4.
Immunogen: Synthesized peptide derived from the human PLD4 Polyclonal
Function 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.
Protein Name 5'-3' Exonuclease Pld4
Choline Phosphatase 4
Phosphatidylcholine-Hydrolyzing Phospholipase D4
Phospholipase D Family Member 4
Phospholipase D4
Pld 4
Database Links Reactome: R-HSA-1483148
Reactome: R-HSA-1855204
Reactome: R-HSA-2029485
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Golgi Apparatus
Trans-Golgi Network Membrane
Nucleus
Early Endosome
Cytoplasmic Vesicle
Phagosome
Activation Of Microglia Induces Translocation Of Pld4 From The Nucleus To The Phagosomes
Alternative Antibody Names Anti-5'-3' Exonuclease Pld4 antibody
Anti-Choline Phosphatase 4 antibody
Anti-Phosphatidylcholine-Hydrolyzing Phospholipase D4 antibody
Anti-Phospholipase D Family Member 4 antibody
Anti-Phospholipase D4 antibody
Anti-Pld 4 antibody
Anti-PLD4 antibody
Anti-C14orf175 antibody
Anti-UNQ2488 antibody
Anti-PRO5775 antibody

Information sourced from Uniprot.org

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