Anti-PLCB4 antibody (STJ191892)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-4 for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLCB4 |
| Gene ID | 5332 |
| Uniprot ID | PLCB4_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | PLCB4 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4Phosphoinositide Phospholipase C-Beta-4Phospholipase C-Beta-4Plc-Beta-4 |
| Database Links | Reactome: R-HSA-112043Reactome: R-HSA-1855204Reactome: R-HSA-416476 |
| Cellular Localisation | Cell Membrane |
| Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-4 antibodyAnti-Phosphoinositide Phospholipase C-Beta-4 antibodyAnti-Phospholipase C-Beta-4 antibodyAnti-Plc-Beta-4 antibodyAnti-PLCB4 antibody |
Information sourced from Uniprot.org