• STJ73669 (8µg/ml) staining of paraffin embedded Human Prostate. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
  • STJ73669 Negative Control showing staining of paraffin embedded Human Prostate, with no primary antibody.
  • STJ73669 (8µg/ml) staining of paraffin embedded Human Placenta. Heat induced antigen retrieval with citrate buffer Ph 6, HRP-staining.
  • STJ73669 Negative Control showing staining of paraffin embedded Human Placenta, with no primary antibody.

Anti-Plasminogen Activator/PLAU antibody (C-Term) (STJ73669)

SKU:
STJ73669-100

£303.50
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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Plasminogen Activator/PLAU (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-8µg/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PLAU
Gene ID: 5328
Uniprot ID: UROK_HUMAN
Immunogen Region: C-Term
Accession Number: NP_002649.1; NP_001138503.1
Specificity: This antibody is expected to recognise both reported isoforms.
Immunogen Sequence: HFLPWIRSHTKEEN
Post Translational Modifications Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Produced as an inactive single-chain protein (pro-uPA or sc-uPA), is processed into the active disulfide-linked two-chain form of PLAU/uPA by a proteolytic event mediated, at least, by TMPRSS4.
Function Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Protein Name Urokinase-Type Plasminogen Activator
U-Plasminogen Activator
Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Secreted
Alternative Antibody Names Anti-Urokinase-Type Plasminogen Activator antibody
Anti-U-Plasminogen Activator antibody
Anti-Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B antibody
Anti-PLAU antibody

Information sourced from Uniprot.org

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