Anti-PKA RII alpha antibody [1B4] (STJA0032691)

Name: Anti-PKA RII alpha antibody [1B4] (STJA0032691)
SKU: STJA0032691
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG1

ImmunogenFull length human recombinant protein of human PRKAR2A produced in 293T cell.

STJA0032691

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Short Description	Mouse monoclonal anti-PKA RII alpha for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P
Host	Mouse
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	1B4
Isotype	IgG1
Conjugation	Unconjugated
Concentration	0.53 mg/mL
Purification	Affinity Purified
Dilution Range	WB 1:500-1:1000 IHC 1:50-1:100
Formulation	Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction	Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Gene Symbol	PRKAR2A
Gene ID	5576
Uniprot ID	KAP2_HUMAN
Immunogen	Full length human recombinant protein of human PRKAR2A produced in 293T cell.

Tissue Specificity	Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Post Translational Modifications	Phosphorylated by the activated catalytic chain.
Function	Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Protein Name	Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit
Database Links	Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-180024 Reactome: R-HSA-381676 Reactome: R-HSA-432040 Reactome: R-HSA-442720 Reactome: R-HSA-5610787 Reactome: R-HSA-9010642 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323 Reactome: R-HSA-983231 Reactome: R-HSA-9856530
Cellular Localisation	Cytoplasm Cell Membrane Colocalizes With Pja2 In The Cytoplasm And The Cell Membrane
Alternative Antibody Names	Anti-Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit antibody Anti-PRKAR2A antibody Anti-PKR2 antibody Anti-PRKAR2 antibody

Information sourced from Uniprot.org