| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PITX1 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
Pitx1 |
| Gene ID: |
18740 |
| Uniprot ID: |
PITX1_MOUSE |
| Immunogen Region: |
N-Term |
| Specificity: |
Specific for PITX1. |
| Immunogen: |
A synthetic peptide from n-terminal region of mouse PITX1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. Can independently activate and synergize with PIT-1 on pituitary-specific target gene promoters, thus may subserve functions in generating both precursor and specific cell phenotypes in the anterior pituitary gland and in several other organs. Can activate pituitary transcription of the proopiomelanocortin gene. |
| Protein Name | Pituitary Homeobox 1Hindlimb-Expressed Homeobox Protein BackfootHomeobox Protein P-OtxHomeobox Protein Pitx1Paired-Like Homeodomain Transcription Factor 1Pituitary Otx-Related Factor |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pituitary Homeobox 1 antibodyAnti-Hindlimb-Expressed Homeobox Protein Backfoot antibodyAnti-Homeobox Protein P-Otx antibodyAnti-Homeobox Protein Pitx1 antibodyAnti-Paired-Like Homeodomain Transcription Factor 1 antibodyAnti-Pituitary Otx-Related Factor antibodyAnti-Pitx1 antibodyAnti-Bft antibodyAnti-Potx antibodyAnti-Ptx1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
