| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phosphatidylinositol 4-kinase beta is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PI4KB |
| Gene ID: |
5298 |
| Uniprot ID: |
PI4KB_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PI4KB at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human PI4KB |
| Function | Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking. May play an important role in the inner ear development. (Microbial infection) Plays an essential role in Aichi virus RNA replication. Recruited by ACBD3 at the viral replication sites. (Microbial infection) Required for cellular spike-mediated entry of human coronavirus SARS-CoV. |
| Protein Name | Phosphatidylinositol 4-Kinase BetaPi4k-BetaPi4kbetaPtdins 4-Kinase BetaNpikPi4k92Pi4kiii |
| Database Links | Reactome: R-HSA-1660514 |
| Cellular Localisation | Endomembrane SystemMitochondrion Outer MembranePeripheral Membrane ProteinRough Endoplasmic Reticulum MembraneGolgi ApparatusGolgi Apparatus MembraneCytoplasmPerinuclear RegionFound In The Outer Membrane Of Mitochondria And Membranes Of The Rough Endoplasmic ReticulumRecruited To The Golgi Complex By The Small Gtpase Arf To Stimulate The Synthesis Of Phosphatidylinositol 45-Bisphosphate (Pip2) On The Golgi ComplexRecruited To The Golgi Apparatus Membrane By Acbd3Gga2 Is Also Involved In The Recruitment |
| Alternative Antibody Names | Anti-Phosphatidylinositol 4-Kinase Beta antibodyAnti-Pi4k-Beta antibodyAnti-Pi4kbeta antibodyAnti-Ptdins 4-Kinase Beta antibodyAnti-Npik antibodyAnti-Pi4k92 antibodyAnti-Pi4kiii antibodyAnti-PI4KB antibodyAnti-PIK4CB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
