Anti-PHOX2B antibody [SQab22261] (STJ16103009)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
ImmunogenSynthetic peptide of Human PHOX2B.
General Information
| Short Description | Rabbit monoclonal anti-PHOX2B for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SQab22261 |
| Conjugation | Unconjugated |
| Purification | Purification with Protein A. |
| Formulation | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Storage Instruction | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PHOX2B |
| Gene ID | 8929 |
| Uniprot ID | PHX2B_HUMAN |
| Immunogen | Synthetic peptide of Human PHOX2B. |
Additional Info
| Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. |
| Protein Name | Paired Mesoderm Homeobox Protein 2bNeuroblastoma PhoxNbphoxPhox2b Homeodomain ProteinPaired-Like Homeobox 2b |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Mesoderm Homeobox Protein 2b antibodyAnti-Neuroblastoma Phox antibodyAnti-Nbphox antibodyAnti-Phox2b Homeodomain Protein antibodyAnti-Paired-Like Homeobox 2b antibodyAnti-PHOX2B antibodyAnti-PMX2B antibody |
Information sourced from Uniprot.org