Anti-Phospho-TOB1-Ser164 antibody (130-179 aa) (STJ90995)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TOB1 around the phosphorylation site of Ser164 at the amino acid range 130-179
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Protein Tob1-Ser164 (130-179 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TOB1 |
| Gene ID | 10140 |
| Uniprot ID | TOB1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TOB1 around the phosphorylation site of Ser164 at the amino acid range 130-179 |
| Immunogen Region | 130-179 aa |
| Specificity | Phospho-TOB1 (S164) Polyclonal Antibody detects endogenous levels of TOB1 protein only when phosphorylated at S164. |
Additional Info
| Post Translational Modifications | Phosphorylated on Ser and Thr residues. |
| Function | Anti-proliferative protein.the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay. |
| Protein Name | Protein Tob1Transducer Of Erbb-2 1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusOnly A Small Fraction Localizes To The Cytoplasm Except In Late S-Phase Where More Than Half Of Proteins Become Cytoplasmic |
| Alternative Antibody Names | Anti-Protein Tob1 antibodyAnti-Transducer Of Erbb-2 1 antibodyAnti-TOB1 antibodyAnti-TOB antibodyAnti-TROB1 antibody |
Information sourced from Uniprot.org