Anti-Phospho-TLN1-Ser425 antibody (STJ196447)

SKU:
STJ196447

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Talin-1-Ser425 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TLN1
Gene ID: 7094
Uniprot ID: TLN1_HUMAN
Specificity: This antibody detects endogenous levels of Human Mouse Rat Talin (phospho-Ser425)
Immunogen: Synthesized phosho peptide around human Talin (Ser425)
Function High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane.
Protein Name Talin-1
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-354192
Reactome: R-HSA-354194
Reactome: R-HSA-372708
Reactome: R-HSA-381038
Reactome: R-HSA-399955
Reactome: R-HSA-445355
Reactome: R-HSA-5674135
Reactome: R-HSA-6802946
Reactome: R-HSA-6802948
Reactome: R-HSA-6802952
Reactome: R-HSA-6802955
Reactome: R-HSA-9649948
Reactome: R-HSA-9656223
Cellular Localisation Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Cell Surface
Cell Junction
Focal Adhesion
Colocalizes With Layn At The Membrane Ruffles
Localized Preferentially In Focal Adhesions Than Fibrillar Adhesions
Alternative Antibody Names Anti-Talin-1 antibody
Anti-TLN1 antibody
Anti-KIAA1027 antibody
Anti-TLN antibody

Information sourced from Uniprot.org

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