Anti-Phospho-TIE1-Tyr1117 antibody (STJA0009945)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TIE1 (Phospho-Tyr1117)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Tyrosine-protein kinase receptor Tie-1-Tyr1117 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIE1 |
| Gene ID | 7075 |
| Uniprot ID | TIE1_HUMAN |
| Immunogen | Synthesized peptide derived from human TIE1 (Phospho-Tyr1117) |
| Specificity | This antibody detects endogenous levels of TIE1 (Phospho-Tyr1117) at Human, Mouse, Rat |
Additional Info
| Tissue Specificity | Specifically expressed in developing vascular endothelial cells. |
| Post Translational Modifications | Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2. |
| Function | Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. |
| Protein Name | Tyrosine-Protein Kinase Receptor Tie-1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Receptor Tie-1 antibodyAnti-TIE1 antibodyAnti-TIE antibody |
Information sourced from Uniprot.org