• Western blot analysis of lysates from Jurkat cells treated with PMA 125ng/ml 30', using TAL-1 (Phospho-Ser122) Antibody. The lane on the right is blocked with the phospho peptide.

Anti-Phospho-TAL1-Ser122 antibody (96-145 aa) (STJ90638)

SKU:
STJ90638

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-T-cell acute lymphocytic leukemia protein 1-Ser122 (96-145 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TAL1
Gene ID: 6886
Uniprot ID: TAL1_HUMAN
Immunogen Region: 96-145 aa
Specificity: Phospho-TAL1 (S122) Polyclonal Antibody detects endogenous levels of TAL1 protein only when phosphorylated at S122.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TAL-1 around the phosphorylation site of Ser122 at the amino acid range 96-145
Post Translational Modifications Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia. Ubiquitinated.subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells.
Function Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.
Protein Name T-Cell Acute Lymphocytic Leukemia Protein 1
Tal-1
Class A Basic Helix-Loop-Helix Protein 17
Bhlha17
Stem Cell Protein
T-Cell Leukemia/Lymphoma Protein 5
Database Links Reactome: R-HSA-8939236
Reactome: R-HSA-9616222
Cellular Localisation Nucleus
Alternative Antibody Names Anti-T-Cell Acute Lymphocytic Leukemia Protein 1 antibody
Anti-Tal-1 antibody
Anti-Class A Basic Helix-Loop-Helix Protein 17 antibody
Anti-Bhlha17 antibody
Anti-Stem Cell Protein antibody
Anti-T-Cell Leukemia/Lymphoma Protein 5 antibody
Anti-TAL1 antibody
Anti-BHLHA17 antibody
Anti-SCL antibody
Anti-TCL5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance