Anti-Phospho-STAT6 antibody (610-660) (STJ502702)

SKU:
STJ502702-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-STAT6 (610-660) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:2, 500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: STAT6
Gene ID: 6778
Uniprot ID: STAT6_HUMAN
Immunogen Region: 610-660
Immunogen: Synthetic peptide taken within amino acid region 610-660 on human Phospho-specific Signal transducer and activator of transcription 6 protein. Phosphorylated Tyrosine 641 residue.
Post Translational Modifications Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14.
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
Protein Name Signal Transducer And Activator Of Transcription 6
Il-4 Stat
Database Links Reactome: R-HSA-186763
Reactome: R-HSA-3249367
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 6 antibody
Anti-Il-4 Stat antibody
Anti-STAT6 antibody

Information sourced from Uniprot.org

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