• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using STAT5B (Phospho-Ser731) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from RAW264.7 cells treated with EGF 200ng/ml 30', using STAT5B (Phospho-Ser731) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of various cells using Phospho-Stat5 (S726/731) Polyclonal Antibody diluted at 1:500

Anti-Phospho-Stat5-Ser726/731 antibody (697-746 aa) (STJ90773)

SKU:
STJ90773

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Signal transducer and activator of transcription 5A and Signal transducer and activator of transcription 5B-Ser726/731 (697-746 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAT5B
STAT5A
Gene ID: 6777
6776
Uniprot ID: STA5B_HUMAN
STA5A_HUMAN
Immunogen Region: 697-746 aa
Specificity: Phospho-Stat5 (S726/731) Polyclonal Antibody detects endogenous levels of Stat5 protein only when phosphorylated at S726/731.
Immunogen: The antiserum was produced against synthesized peptide derived from the human STAT5B around the phosphorylation site of Ser731 at the amino acid range 697-746
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Protein Name Signal Transducer And Activator Of Transcription 5a
Database Links Reactome: R-HSA-1170546
Reactome: R-HSA-1251985
Reactome: R-HSA-1266695
Reactome: R-HSA-1433557
Reactome: R-HSA-1839117
Reactome: R-HSA-186763
Reactome: R-HSA-2586552
Reactome: R-HSA-512988
Reactome: R-HSA-8854691
Reactome: R-HSA-8983432
Reactome: R-HSA-8985947
Reactome: R-HSA-9020558
Reactome: R-HSA-9020958
Reactome: R-HSA-9027283
Reactome: R-HSA-9645135
Reactome: R-HSA-9670439
Reactome: R-HSA-982772
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 5a antibody
Anti-STAT5A antibody
Anti-STAT5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance