Anti-Phospho-SLC6A3-Thr53 antibody (STJA0003618)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Thr53 conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Dopamine Transporter-Thr53 for use in WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Slc6a3 |
| Gene ID | 24898 |
| Uniprot ID | SC6A3_RAT |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr53 conjugated to KLH. |
Additional Info
| Tissue Specificity | Brain. Expressed in the substantia nigra and ventral tegmental area, regions that contain dopaminergic cell bodies. |
| Function | Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling. |
| Protein Name | Sodium-Dependent Dopamine TransporterDa TransporterDatSolute Carrier Family 6 Member 3 |
| Database Links | Reactome: R-RNO-379401Reactome: -RNO-442660 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionNeuron ProjectionAxonLocalizes To Neurite Tips In Neuronal CellsColocalizes With Septin4 At Axon TerminalsEspecially At The Varicosities |
| Alternative Antibody Names | Anti-Sodium-Dependent Dopamine Transporter antibodyAnti-Da Transporter antibodyAnti-Dat antibodyAnti-Solute Carrier Family 6 Member 3 antibodyAnti-Slc6a3 antibody |
Information sourced from Uniprot.org