Anti-Phospho-RSK4-Ser232 antibody [R04-8D6] (STJA0033902)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser235 of human RSK4
General Information
| Short Description | Rabbit monoclonal anti-Phospho-RSK4-Ser232 for use in WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-8D6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RPS6KA6 |
| Gene ID | 27330 |
| Uniprot ID | KS6A6_HUMAN |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser235 of human RSK4 |
Additional Info
| Post Translational Modifications | Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells. |
| Function | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. |
| Protein Name | Ribosomal Protein S6 Kinase Alpha-6S6k-Alpha-690 Kda Ribosomal Protein S6 Kinase 6P90-Rsk 6P90rsk6Ribosomal S6 Kinase 4Rsk-4Pp90rsk4 |
| Database Links | Reactome: R-HSA-437239Reactome: R-HSA-442742Reactome: R-HSA-444257 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Cytosolic |
| Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Alpha-6 antibodyAnti-S6k-Alpha-6 antibodyAnti-90 Kda Ribosomal Protein S6 Kinase 6 antibodyAnti-P90-Rsk 6 antibodyAnti-P90rsk6 antibodyAnti-Ribosomal S6 Kinase 4 antibodyAnti-Rsk-4 antibodyAnti-Pp90rsk4 antibodyAnti-RPS6KA6 antibodyAnti-RSK4 antibody |
Information sourced from Uniprot.org