| Short Description : | Rabbit polyclonal anti-Phospho-Tyrosine-protein kinase transmembrane receptor ROR2-Ser449 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ROR2 |
| Gene ID: | 4920 |
| Uniprot ID: | ROR2_HUMAN |
| Immunogen: | Synthesized peptide derived from human ROR2 (Phospho-Ser449) |
| Specificity: | This antibody detects endogenous levels of ROR2 (Phospho-Ser449) at Human, Mouse, Rat |
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. |
| Protein Name | Tyrosine-Protein Kinase Transmembrane Receptor Ror2Neurotrophic Tyrosine Kinase - Receptor-Related 2 |
| Database Links | Reactome: R-HSA-4086400Reactome: R-HSA-5140745 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Transmembrane Receptor Ror2 antibodyAnti-Neurotrophic Tyrosine Kinase - Receptor-Related 2 antibodyAnti-ROR2 antibodyAnti-NTRKR2 antibody |
Information sourced from Uniprot.org
