Anti-Phospho-PRKAR2B-Ser113 antibody (79-128 aa) (STJ90520)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PKA-R2 beta around the phosphorylation site of Ser113 at the amino acid range 79-128
General Information
| Short Description | Rabbit polyclonal anti-Phospho-cAMP-dependent protein kinase type II-beta regulatory subunit-Ser113 (79-128 aa) for use in WB, IHC, IF and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related re |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRKAR2B |
| Gene ID | 5577 |
| Uniprot ID | KAP3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PKA-R2 beta around the phosphorylation site of Ser113 at the amino acid range 79-128 |
| Immunogen Region | 79-128 aa |
| Specificity | Phospho-PKA II Beta reg (S113) Polyclonal Antibody detects endogenous levels of PKA II Beta reg protein only when phosphorylated at S113. |
Additional Info
| Post Translational Modifications | Phosphorylated by the activated catalytic chain. |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
| Protein Name | Camp-Dependent Protein Kinase Type Ii-Beta Regulatory Subunit |
| Database Links | Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-180024Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-381676Reactome: R-HSA-432040Reactome: R-HSA-442720Reactome: R-HSA-5610787Reactome: R-HSA-5620912Reactome: R-HSA-8854518Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-983231Reactome: R-HSA-9856530 |
| Cellular Localisation | CytoplasmCell MembraneColocalizes With Pja2 In The Cytoplasm And At The Cell Membrane |
| Alternative Antibody Names | Anti-Camp-Dependent Protein Kinase Type Ii-Beta Regulatory Subunit antibodyAnti-PRKAR2B antibody |
Information sourced from Uniprot.org