Anti-Phospho-PLCG2-Tyr759 antibody (STJ196387)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized phosho peptide around human PLC Gamma 2 (Tyr759)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2-Tyr759 for use in WB, IF, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000IF ICC 1:50-200ELISA 1:2000-20000IHC-P 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLCG2 |
| Gene ID | 5336 |
| Uniprot ID | PLCG2_HUMAN |
| Immunogen | Synthesized phosho peptide around human PLC Gamma 2 (Tyr759) |
| Specificity | This antibody detects endogenous levels of Human Mouse PLC Gamma 2 (phospho-Tyr759) |
Additional Info
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Gamma-2Phosphoinositide Phospholipase C-Gamma-2Phospholipase C-IvPlc-IvPhospholipase C-Gamma-2Plc-Gamma-2 |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-166016Reactome: R-HSA-1855204Reactome: R-HSA-202433Reactome: R-HSA-2029485Reactome: R-HSA-2424491Reactome: R-HSA-2871796Reactome: R-HSA-2871809Reactome: R-HSA-5607764Reactome: R-HSA-5621480Reactome: R-HSA-9027277Reactome: R-HSA-9664323Reactome: R-HSA-9679191Reactome: R-HSA-9680350Reactome: R-HSA-983695 |
| Cellular Localisation | Membrane Raft |
| Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Gamma-2 antibodyAnti-Phosphoinositide Phospholipase C-Gamma-2 antibodyAnti-Phospholipase C-Iv antibodyAnti-Plc-Iv antibodyAnti-Phospholipase C-Gamma-2 antibodyAnti-Plc-Gamma-2 antibodyAnti-PLCG2 antibody |
Information sourced from Uniprot.org