Anti-Phospho-PGCA antibody (500-550) {Biotin} (STJ502628)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 500-550 on human Atrial natriuretic peptide receptor 1 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-Phospho-PGCA (500-550) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.55-0.75 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR1 |
| Gene ID | 4881 |
| Uniprot ID | ANPRA_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 500-550 on human Atrial natriuretic peptide receptor 1 protein. |
| Immunogen Region | 500-550 |
Additional Info
| Post Translational Modifications | Phosphorylation of the protein kinase-like domain is required for full activation by ANP. |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
| Protein Name | Atrial Natriuretic Peptide Receptor 1Atrial Natriuretic Peptide Receptor Type AAnp-AAnpr-ANpr-AGuanylate Cyclase AGc-A |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 1 antibodyAnti-Atrial Natriuretic Peptide Receptor Type A antibodyAnti-Anp-A antibodyAnti-Anpr-A antibodyAnti-Npr-A antibodyAnti-Guanylate Cyclase A antibodyAnti-Gc-A antibodyAnti-NPR1 antibodyAnti-ANPRA antibody |
Information sourced from Uniprot.org