Anti-Phospho-PFKFB2-S483 antibody (STJ117882)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Phospho-PFKFB2-S483 antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PFKFB2 |
| Gene ID | 5208 |
| Uniprot ID | F262_HUMAN |
| Immunogen Sequence | NYSVG |
| Specificity | A synthetic phosphorylated peptide around S483 of human PFKFB2 (NP_006203.2). |
Additional Info
| Tissue Specificity | Heart. |
| Post Translational Modifications | Phosphorylation by AMPK stimulates activity. |
| Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
| Protein Name | 6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 26pf-2-K/Fru-2 -6-P2ase 2Pfk/Fbpase 26pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase |
| Database Links | Reactome: R-HSA-9634600 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase 2 antibodyAnti-Pfk/Fbpase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase antibodyAnti-PFKFB2 antibody |
Information sourced from Uniprot.org