• Western blot analysis of lysate from K562 cells, uisng phospho-PDLIM5 (Phospho-Tyr251) antibody.
  • Western blot analysis of K562 cells using Phospho-PDLIM5 (Y251) Polyclonal Antibody

Anti-Phospho-PDLIM5-Tyr251 antibody (STJ90383)

SKU:
STJ90383

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-PDZ and LIM domain protein 5-Tyr251 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDLIM5
Gene ID: 10611
Uniprot ID: PDLI5_HUMAN
Specificity: Phospho-PDLIM5 (Y251) Polyclonal Antibody detects endogenous levels of PDLIM5 protein only when phosphorylated at Y251.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human PDLIM5 (phospho Tyr251)
Function May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation.
Protein Name Pdz And Lim Domain Protein 5
Enigma Homolog
Enigma-Like Pdz And Lim Domains Protein
Database Links Reactome: R-HSA-6794361
Cellular Localisation Postsynaptic Density
Presynapse
Postsynapse
Cytoplasm
Cytosol
Detected Both At Presynaptic And Postsynaptic Sites
Exclusively At Excitatory Synapses
But Not Inhibitory Synapses
In Hippocampal Neurons
Alternative Antibody Names Anti-Pdz And Lim Domain Protein 5 antibody
Anti-Enigma Homolog antibody
Anti-Enigma-Like Pdz And Lim Domains Protein antibody
Anti-PDLIM5 antibody
Anti-ENH antibody
Anti-L9 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance