Anti-Phospho-PDE11A antibody (100-200) (STJ506100)

Name: Anti-Phospho-PDE11A antibody (100-200) (STJ506100)
SKU: STJ506100-100
Price: 597 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 100-200 on rat PDE11A protein. Phosphorylated Ser 163.

STJ506100-100

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Short Description	Rabbit polyclonal antibody anti-Phospho-PDE11A (100-200) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IP/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.5-1.5 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500-1:5, 000 ELISA: 1:50, 000 IP: 1:200
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	Pde11a
Gene ID	140928
Uniprot ID	PDE11_RAT
Immunogen	Synthetic peptide taken within amino acid region 100-200 on rat PDE11A protein. Phosphorylated Ser 163.
Immunogen Region	100-200

Tissue Specificity	Isoform 1 is expressed in brain, heart, kidney and liver, but not in prostate. Isoform 2 is specifically expressed in testis. Isoform 3 is expressed in various tissues including brain, lung, skeletal muscle, spleen, testis and prostate.
Function	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
Protein Name	Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a Camp And Cgmp Phosphodiesterase 11a
Database Links	Reactome: R-RNO-418457 Reactome: -RNO-418555
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a antibody Anti-Camp And Cgmp Phosphodiesterase 11a antibody Anti-Pde11a antibody

Information sourced from Uniprot.org