Anti-Phospho-PANK4-Thr63 antibody (STJA0003740)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Thr63 conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-Phospho-PanK4-Thr63 for use in WB in Mouse, Hamster and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Mouse/Hamster/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Pank4 |
| Gene ID | 269614 |
| Uniprot ID | PANK4_MOUSE |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr63 conjugated to KLH. |
Additional Info
| Tissue Specificity | Expressed in liver, kidney, brain cortex and eye lens (at protein level). |
| Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels. |
| Protein Name | 4'-Phosphopantetheine PhosphataseInactive Pantothenic Acid Kinase 4Mpank4 |
| Database Links | Reactome: R-MMU-199220 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-4'-Phosphopantetheine Phosphatase antibodyAnti-Inactive Pantothenic Acid Kinase 4 antibodyAnti-Mpank4 antibodyAnti-Pank4 antibody |
Information sourced from Uniprot.org