• Western blot analysis of lysates from HeLa cells treated with TSA 400nM 24H, using NCoA2 (Phospho-Ser736) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NCoA2 (Phospho-Ser736) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-NCOA2-Ser736 antibody (702-751 aa) (STJ90985)

SKU:
STJ90985

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Nuclear receptor coactivator 2-Ser736 (702-751 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NCOA2
Gene ID: 10499
Uniprot ID: NCOA2_HUMAN
Immunogen Region: 702-751 aa
Specificity: Phospho-GRIP-1 (S736) Polyclonal Antibody detects endogenous levels of GRIP-1 protein only when phosphorylated at S736.
Immunogen: The antiserum was produced against synthesized peptide derived from the human NCoA2 around the phosphorylation site of Ser736 at the amino acid range 702-751
Function Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC1 expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK-BMAL1 heterodimer.
Protein Name Nuclear Receptor Coactivator 2
Ncoa-2
Class E Basic Helix-Loop-Helix Protein 75
Bhlhe75
Transcriptional Intermediary Factor 2
Htif2
Database Links Reactome: R-HSA-1368082
Reactome: R-HSA-1368108
Reactome: R-HSA-159418
Reactome: R-HSA-192105
Reactome: R-HSA-193368
Reactome: R-HSA-193807
Reactome: R-HSA-1989781
Reactome: R-HSA-211976
Reactome: R-HSA-2151201
Reactome: R-HSA-2426168
Reactome: R-HSA-3214847
Reactome: R-HSA-381340
Reactome: R-HSA-3899300
Reactome: R-HSA-400206
Reactome: R-HSA-400253
Reactome: R-HSA-5625886
Reactome: R-HSA-9018519
Reactome: R-HSA-9707564
Reactome: R-HSA-9707616
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Nuclear Receptor Coactivator 2 antibody
Anti-Ncoa-2 antibody
Anti-Class E Basic Helix-Loop-Helix Protein 75 antibody
Anti-Bhlhe75 antibody
Anti-Transcriptional Intermediary Factor 2 antibody
Anti-Htif2 antibody
Anti-NCOA2 antibody
Anti-BHLHE75 antibody
Anti-SRC2 antibody
Anti-TIF2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance