| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-N-acetyl-D-glucosamine kinase-Ser74 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NAGK |
| Gene ID: |
55577 |
| Uniprot ID: |
NAGK_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Human, Mouse, Rat NAGK (phospho-Ser74) |
| Immunogen: |
Synthesized peptide derived from human NAGK (phospho-Ser74) |
| Function | Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has N-acetylmannosamine (ManNAc) kinase activity. Also involved in innate immunity by promoting detection of bacterial peptidoglycan by NOD2: acts by catalyzing phosphorylation of muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, to generate 6-O-phospho-muramyl dipeptide, which acts as a direct ligand for NOD2. |
| Protein Name | N-Acetyl-D-Glucosamine KinaseN-Acetylglucosamine KinaseGlcnac KinaseMuramyl Dipeptide KinaseN-Acetyl-D-Mannosamine Kinase |
| Database Links | Reactome: R-HSA-446210 |
| Alternative Antibody Names | Anti-N-Acetyl-D-Glucosamine Kinase antibodyAnti-N-Acetylglucosamine Kinase antibodyAnti-Glcnac Kinase antibodyAnti-Muramyl Dipeptide Kinase antibodyAnti-N-Acetyl-D-Mannosamine Kinase antibodyAnti-NAGK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
