Anti-Phospho-MYBL2-Thr494/497 antibody (STJA0010052)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human B-Myb (Phospho Thr494/497)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Myb-related protein B-Thr494/497 for use in IHC and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYBL2 |
| Gene ID | 4605 |
| Uniprot ID | MYBB_HUMAN |
| Immunogen | Synthesized peptide derived from human B-Myb (Phospho Thr494/497) |
| Specificity | This antibody detects endogenous levels of B-Myb (Phospho Thr494/497) Rabbit pAb at Human, Mouse |
Additional Info
| Post Translational Modifications | Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity. |
| Function | Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene. |
| Protein Name | Myb-Related Protein BB-MybMyb-Like Protein 2 |
| Database Links | Reactome: R-HSA-1362300Reactome: R-HSA-156711Reactome: R-HSA-8869496 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Myb-Related Protein B antibodyAnti-B-Myb antibodyAnti-Myb-Like Protein 2 antibodyAnti-MYBL2 antibodyAnti-BMYB antibody |
Information sourced from Uniprot.org