Anti-Phospho-MEF2D-Ser444 antibody (410-459 aa) (STJ90325)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MEF2D around the phosphorylation site of Ser444 at the amino acid range 410-459
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Myocyte-specific enhancer factor 2D-Ser444 (410-459 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MEF2D |
| Gene ID | 4209 |
| Uniprot ID | MEF2D_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MEF2D around the phosphorylation site of Ser444 at the amino acid range 410-459 |
| Immunogen Region | 410-459 aa |
| Specificity | Phospho-MEF-2D (S444) Polyclonal Antibody detects endogenous levels of MEF-2D protein only when phosphorylated at S444. |
Additional Info
| Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTAAT(4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis. |
| Protein Name | Myocyte-Specific Enhancer Factor 2d |
| Database Links | Reactome: R-HSA-2151201Reactome: R-HSA-400253Reactome: R-HSA-525793Reactome: R-HSA-9031628Reactome: R-HSA-9707616 |
| Cellular Localisation | NucleusTranslocated By Hdac4 To Nuclear Dots |
| Alternative Antibody Names | Anti-Myocyte-Specific Enhancer Factor 2d antibodyAnti-MEF2D antibody |
Information sourced from Uniprot.org