• Western blot analysis of extracts of Jurkat cells, using Phospho-MAX-S11 antibody (STJ22282) at 1:1000 dilution. Jurkat cells were treated by serum-starvation overnight. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA.
  • Western blot analysis of lysates from Jurkat cells, using Phospho-MAX-S11 Rabbit polyclonal antibody (STJ22282) at 1:1000 dilution. Jurkat cells were treated by serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% BSA.

Anti-Phospho-MAX-S11 antibody (STJ22282)

SKU:
STJ22282

£212.50 - £501.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-MAX-S11 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAX
Gene ID: 4149
Uniprot ID: MAX_HUMAN
Immunogen: A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3).
Immunogen Sequence: VESDE
Tissue Specificity High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Post Translational Modifications Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.
Function Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Protein Name Protein Max
Class D Basic Helix-Loop-Helix Protein 4
Bhlhd4
Myc-Associated Factor X
Database Links Reactome: R-HSA-1362277
Reactome: R-HSA-69202
Reactome: R-HSA-69656
Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Cell Projection
Dendrite
Alternative Antibody Names Anti-Protein Max antibody
Anti-Class D Basic Helix-Loop-Helix Protein 4 antibody
Anti-Bhlhd4 antibody
Anti-Myc-Associated Factor X antibody
Anti-MAX antibody
Anti-BHLHD4 antibody

Information sourced from Uniprot.org

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