| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat/Bovine/Chicken/Human/Xenopus/Zebrafish |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-MARCKS-Ser152/156 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: |
This antibody was antigen affinity purified from pooled serum. |
| Dilution Range: |
WB 1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MarcksUniprot ID=MARCS_RAT" |
| Immunogen: |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser152/156 conjugated to KLH. |
| Tissue Specificity | Highest levels found in spleen and brain. Intermediate levels seen in thymus, ovary, lung and heart. Very low levels seen in kidney, skeletal muscle and liver. |
| Post Translational Modifications | Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity. |
| Function | MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. |
| Protein Name | Myristoylated Alanine-Rich C-Kinase SubstrateMarcksProtein Kinase C Substrate 80 Kda Protein |
| Cellular Localisation | CytoplasmCytoskeletonMembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Myristoylated Alanine-Rich C-Kinase Substrate antibodyAnti-Marcks antibodyAnti-Protein Kinase C Substrate 80 Kda Protein antibodyAnti-Marcks antibodyAnti-Macs antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
