Anti-Phospho-MAP3K2-Ser520 antibody (STJA0009920)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MAP3K2 (Phospho-Ser520)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Mitogen-activated protein kinase kinase kinase 2-Ser520 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAP3K2 |
| Gene ID | 10746 |
| Uniprot ID | M3K2_HUMAN |
| Immunogen | Synthesized peptide derived from human MAP3K2 (Phospho-Ser520) |
| Specificity | This antibody detects endogenous levels of MAP3K2 (Phospho-Ser520) at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Autophosphorylated. Ubiquitination by XIAP/BIRC4 does not lead to proteasomal degradation. |
| Function | Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 2Mapk/Erk Kinase Kinase 2Mek Kinase 2Mekk 2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusUpon Egf StimulationTranslocates Into The Nucleus |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 antibodyAnti-Mapk/Erk Kinase Kinase 2 antibodyAnti-Mek Kinase 2 antibodyAnti-Mekk 2 antibodyAnti-MAP3K2 antibodyAnti-MAPKKK2 antibodyAnti-MEKK2 antibody |
Information sourced from Uniprot.org