| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-Lymphocyte cytosolic protein 2-Ser376 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LCP2 |
| Gene ID: |
3937 |
| Uniprot ID: |
LCP2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Human Mouse SLP-76 (phospho-Ser376) |
| Immunogen: |
Synthesized phosho peptide around human SLP-76 (Ser376) |
| Post Translational Modifications | Phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2. SYK-dependent phosphorylation is required for recruitment of PI3K signaling components. |
| Function | Involved in T-cell antigen receptor mediated signaling. |
| Protein Name | Lymphocyte Cytosolic Protein 2Sh2 Domain-Containing Leukocyte Protein Of 76 KdaSlp-76 Tyrosine PhosphoproteinSlp76 |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-202433Reactome: R-HSA-2424491Reactome: R-HSA-2871796Reactome: R-HSA-2871809 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Lymphocyte Cytosolic Protein 2 antibodyAnti-Sh2 Domain-Containing Leukocyte Protein Of 76 Kda antibodyAnti-Slp-76 Tyrosine Phosphoprotein antibodyAnti-Slp76 antibodyAnti-LCP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
