Anti-Phospho-KIF1B-Ser1487 antibody (STJ196344)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized phosho peptide around human KIF1B (Ser1487)
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Kinesin-like protein KIF1B-Ser1487 for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIF1B |
| Gene ID | 23095 |
| Uniprot ID | KIF1B_HUMAN |
| Immunogen | Synthesized phosho peptide around human KIF1B (Ser1487) |
| Specificity | This antibody detects endogenous levels of Human KIF1B (phospho-Ser1487) |
Additional Info
| Function | Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria. |
| Protein Name | Kinesin-Like Protein Kif1bKlp |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonHas A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With MicrotubulesIsoform 2: Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneAssociates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal MicrotubulesIsoform 3: MitochondrionAssociates With Mitochondria And Mediates Their Movement Along Microtubules |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif1b antibodyAnti-Klp antibodyAnti-KIF1B antibodyAnti-KIAA0591 antibodyAnti-KIAA1448 antibody |
Information sourced from Uniprot.org