Anti-Phospho-HRH1-Ser398 antibody (364-413 aa) (STJ91347)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Histamine H1 Receptor around the phosphorylation site of Ser398 at the amino acid range 364-413
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Histamine H1 receptor-Ser398 (364-413 aa) for use in IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HRH1 |
| Gene ID | 3269 |
| Uniprot ID | HRH1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Histamine H1 Receptor around the phosphorylation site of Ser398 at the amino acid range 364-413 |
| Immunogen Region | 364-413 aa |
| Specificity | Phospho-Histamine H1 Receptor (S398) Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein only when phosphorylated at S398. |
Additional Info
| Function | G-protein-coupled receptor for histamine, a biogenic amine that functions as an immune modulator and a neurotransmitter. Through the H1 receptor, histamine mediates the contraction of smooth muscles and increases capillary permeability due to contraction of terminal venules. Also mediates neurotransmission in the central nervous system and thereby regulates circadian rhythms, emotional and locomotor activities as well as cognitive functions. |
| Protein Name | Histamine H1 ReceptorH1-RH1rHh1r |
| Database Links | Reactome: R-HSA-390650Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Histamine H1 Receptor antibodyAnti-H1-R antibodyAnti-H1r antibodyAnti-Hh1r antibodyAnti-HRH1 antibody |
Information sourced from Uniprot.org